[S]ubject matters in general do not exist. There are no subject matters; no branches of learning—or, rather, of inquiry: there are only problems, and the urge to solve them.
As a rule, begin my lectures on Scientific Method by telling my students that scientific method does not exist. ...having been ...the one and only professor of this non-existent subject within the British Commonwealth.
Darwinism is not a testable scientific theory, but a metaphysical research program.
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Unsourced variant: Evolution is not a fact. Evolution doesn't even qualify as a theory or as a hypothesis. It is a metaphysical research program, and it is not really testable science.
One of the ideas I had discussed in The Poverty of Historicism was the influence of a prediction upon the event predicted. I had called this the "Oedipus effect", because the oracle played a most important role in the sequence of events which led to the fulfilment of its prophecy. ... For a time I thought that the existence of the Oedipus effect distinguished the social from the natural sciences. But in biology, too—even in molecular biology—expectations often play a role in bringing about what has been expected.
There are all kinds of sources of our knowledge; but none has authority ... The fundamental mistake made by the philosophical theory of the ultimate sources of our knowledge is that it does not distinguish clearly enough between questions of origin and questions of validity.
I may illustrate this by two very different examples of human behaviour: that of a man who pushes a child into the water with the intention of drowning it; and that of a man who sacrifices his life in an attempt to save the child. Each of these two cases can be explained with equal ease in Freudian and in Adlerian terms. According to Freud the first man suffered from repression (say, of some component of his Oedipus complex), while the second man had achieved sublimation. According to Adler the first man suffered from feelings of inferiority (producing perhaps the need to prove to himself that he dared to commit some crime), and so did the second man (whose need was to prove to himself that he dared to rescue the child). I could not think of any human behaviour which could not be interpreted in terms of either theory. It was precisely this fact — that they always fitted, that they were always confirmed — which in the eyes of their admirers constituted the strongest argument in favour of these theories. It began to dawn on me that this apparent strength was in fact their weakness.
As for Adler, I was much impressed by a personal experience. Once, in 1919, I reported to him a case which to me did not seem particularly Adlerian, but which he found no difficulty in analyzing in terms of his theory of inferiority feelings, although he had not even seen the child. Slightly shocked, I asked him how he could be so sure. "Because of my thousandfold experience," he replied; whereupon I could not help saying: "And with this new case, I suppose, your experience has become thousand-and-one-fold."