I maintain that in every special natural doctrine only so much science proper is to be met with as mathematics; for... science proper, especially of nature, requires a pure portion, lying at the foundation of the empirical, and based upon à priori knowledge of natural things. ...the conception should be constructed. But the cognition of the reason through construction of conceptions is mathematical. A pure philosophy of nature in general, namely, one that only investigates what constitutes a nature in general, may thus be possible without mathematics; but a pure doctrine of nature respecting determinate natural things (corporeal doctrine and mental doctrine), is only possible by means of mathematics; and as in every natural doctrine only so much science proper is to be met with therein as there is cognition à priori, a doctrine of nature can only contain so much science proper as there is in it of applied mathematics.