We don't need fossils - the case for evolution is watertight without them; so it is paradoxical to use gaps in the fossil record as though they were evidence against evolution.

Unfortunately, instead of working out that they have probably misunderstood evolution, creationists conclude, instead, that evolution must be false.

We are survival machines-robot vehicles blindly programmed to preserve the selfish molecules known as genes. This is a truth which still fills me with astonishment.

Living organisms had existed on earth, without ever knowing why, for over three thousand million years before the truth finally dawned on one of them. His name was Charles Darwin. To be fair, others had had inklings of the truth, but it was Darwin who first put together a coherent and tenable account of why we exist.

We no longer have to resort to superstition when faced with the deep problems: Is there a meaning to life? What are we for? What is man?

Today the theory of evolution is about as much open to doubt as the theory that the earth goes round the sun, but the full implications of Darwin's revolution have yet to be widely realized.

The argument of this book is that we, and all other animals, are machines created by our genes.

I am not advocating a morality based on evolution. I am saying how things have evolved. I am not saying how we humans morally ought to behave.

Let us try to teach generosity and altruism, because we are born selfish. Let us understand what our own selfish genes are up to, because we may then at least have a chance to upset their designs, something that no other species has ever aspired to do.

The individual selectionist would admit that groups do indeed die out, and that whether or not a group goes extinct may be influenced by the behaviour of the individuals in that group. He might even admit that if only the individuals in a group had the gift of foresight they could see that in the long run their own best interests lay in restraining their selfish greed, to prevent the destruction of the whole group. How many times must this have been said in recent years to the working people of Britain? But group extinction is a slow process compared with the rapid cut and thrust of individual competition. Even while the group is going slowly and inexorably downhill, selfish individuals prosper in the short term at the expense of altruists. The citizens of Britain may or may not be blessed with foresight, but evolution is blind to the future.

Darwin's 'survival of the fittest' is really a special case of a more general law of survival of the stable. The universe is populated by stable things. The universe is populated by stable things. A stable thing is a collection of atoms that is permanent enough or common enough to deserve a name. It may be a unique collection of atoms, such as the Matterhorn, that lasts long enough to be worth naming. Or it may be a class of entities, such as rain drops, that come into existence at a sufficiently high rate to deserve a collective name, even if any one of them is short-lived.

They are in you and me; they created us, body and mind; and their preservation is the ultimate rationale for our existence. They have come a long way, those replicators. Now they go by the name of genes, and we are their survival machines.

Genes do indirectly control the manufacture of bodies, and the influence is strictly one way: acquired characteristics are not inherited. No matter how much knowledge and wisdom you acquire during your life, not one jot will be passed on to your children by genetic means. Each new generation starts from scratch.

No doubt some of your cousins and great-uncles died in childhood, but not a single one of your ancestors did. Ancestors just don't die young!

Survival machines that can simulate the future are one jump ahead of survival machines that who can only learn of the basis of trial and error. The trouble with overt trial is that it takes time and energy. The trouble with overt error is that it is often fatal. ...The evolution of the capacity to simulate seems to have culminated in subjective consciousness. Why this should have happened is, to me, the most profound mystery facing modern biology.

The genes are the master programmers, and they are programming for their lives.

The selfish gene theory is Darwin's theory, expressed in a way that Darwin did not choose but whose aptness, I should like to think, he would instantly have recognized and delighted in. It is in fact a logical outgrowth of orthodox neo-Darwinism, but expressed as a novel image. Rather than focus on the individual organism, it takes a gene's eye view of nature. It is a different way of seeing, not a different theory.

The remedy for loneliness is human fellowship, the warmth of real, live, flesh-and-blood companions and loved-ones; not prating in a vacuum to an imaginary friend for whose existence there is no vestige of serious evidence. Even an AI robot is better than that. At least ChatGPT exists, really talks back at you, will actually hold a friendly conversation. But talk to the imaginary friend which is God (Allah, Virgin Mary, Lord Krishna, Thor, Zeus, Mithras, name yours) and the only reply you'll get is conjured within your own imagination. You'll be talking to yourself, which is really rather sad, and hardly an antidote to loneliness. No Satisfying Alternative to Religion? Try Reality.

I speak as a biologist. There aren't many absolutely clear distinctions in biology. Mostly what we have is a spectrum. But the male-female divide is exceptional in biology. It really is a true binary.

I do feel visceral revulsion at the burka because for me it is a symbol of the oppression of women.

As a liberal I would hesitate to propose a blanket ban on any style of dress because of the implications for individual liberty and freedom of choice.

Every person I met believes if there is any disagreement between the Koran and science, then the Koran wins. It's just utterly deplorable. These are now British children who are having their minds stuffed with alien rubbish. Occasionally, my colleagues lecturing in universities lament having undergraduate students walk out of their classes when they talk about evolution. This is almost entirely Muslims.

I can't be sure God does not exist... On a scale of seven, where one means I know he exists, and seven I know he doesn't, I call myself a six... That doesn't mean I'm absolutely confident, that I absolutely know, because I don't.

I am often accused of expressing contempt and despising religious people. I don't despise religious people, I despise what they stand for. I like to quote the British journalist Johann Hari who said, "I have so much respect for you, that I cannot respect your ridiculous ideas."

I don't believe you until you tell me, do you really believe, for example, if they say they are Catholic, "Do you really believe that when a priest blesses a wafer, it turns into the body of Christ? Are you seriously telling me you believe that? Are you seriously saying that wine turns into blood?" Mock them. Ridicule them. In public. Don't fall for the convention that we're all too polite to talk about religion. Religion is not off the table. Religion is not off limits. Religion makes specific claims about the universe which need to be substantiated and need to be challenged and, if necessary, need to be ridiculed with contempt.

I am extremely pleased by Daniel Fincke's article, which says exactly what I SHOULD have said and, to my regret, didn't make sufficiently clear in my Reason Rally speech. The best way to summarise it would be to modify the quotation from Johann Hari. Johann said, "I respect you too much to respect your ridiculous beliefs". From now on, my version will be, "I respect you too much to accept that you really believe anything so ridiculous as you claim. Please either defend those beliefs and explain why they are not ridiculous, or else declare that you do not hold them and publicly disown the church to which you claim loyalty."

What I can't understand is why you can't see the extraordinary beauty of the idea that life started from nothing - that is such a staggering, elegant, beautiful thing, why would you want to clutter it up with something so messy as a God?

I'm not clever enough to be a physicist. When asked about why he chose to become a biologist.

I am very conscious that you can't condemn people of an earlier era by the standards of ours. Just as we don't look back at the 18th and 19th centuries and condemn people for racism in the same way as we would condemn a modern person for racism, I look back a few decades to my childhood and see things like caning, like mild pedophilia, and can't find it in me to condemn it by the same standards as I or anyone would today.

Such delusions of grandeur to think that a God with a hundred billion galaxies on his mind would give a tuppenny damn who you sleep with, or indeed whether you believe in him.

Evidence is the only good reason to believe anything.

Moral philosophers say things like, 'What is actually wrong with cannibalism?' There are two ways of responding to that: one is to shrink back in horror and say, 'Cannibalism! Cannibalism! We can't talk about cannibalism!' The other is to say, 'Well, actually, what is wrong with cannibalism?' Then you work it out and you tease it out and you decide yes, actually, cannibalism is wrong, but for the following reasons. So I'd like to think that my moral values at least partly come from reasoning. Trying to suppress the gut reaction as much as possible.

Eternity is best spent under a general anesthetic - which is what is going to happen.

Whenever a system of communication evolves, there is always the danger that some will exploit the system for their own ends.